CASSAVA TOXICITY AND DETOXIFICATION


1.0  INTRODUCTION
The main toxic component which occurs in varying amounts in all parts of the cassava plant is known as linamarin (Philbricket al.,1977). It often coexists with its methyl homologue called methyl – linamarian or lotaustralin.Linamarin is a cyanogenic glucoside which is converted to toxic hydrocyanic acid or prussic acid when it comes into contact with linamarase, an enzyme that is released when the cells of cassava roots are ruptured. Otherwise, linamarin is a rather stable compound which is not changed by boiling the cassava. If it is absorbed from the gut to the blood as the intact glucoside, it is probably excreted uncharged in the urine without causing any harm to the organism.

However, ingested linamarin can liberate cyanide in the gut during digestion. Hydrocyanic acid or HCN is a volatile compound. It evaporates rapidly in the air at a temperature of 25.7oC ( Bokanga, 1995) and dissolves readily in water. It may easily be lost during transport, storage and analysis of specimens. The normal range of cyanogenic content of cassava tubers falls between 15 and 400mg HCN/kg fresh weight (Adindu,1973). The concentration varies greatly and also with environmental and cultural conditions. The concentration of the cyanogenicglucosides increases from the center of the tuber outwards.
The objective of this is to enumerate cassava toxicity and detoxification.
2.0  LITERATURE REVIEW
Cassava (Manihotesculenta) is the staple food of millions of people in the tropics of both hemispheres, particularly South and Central American , Central and West African and South – East Asia. It is known as to have been domesticated independently in central America as well as in south America but introduced from South America to central America, seems more likely. It was taken to West African from Brazil by the Portuguese in the sixteenth century.
Cassava plant is a shrubby, short – lived perennial, growing to a height of 3m or more with an erect stem, marked by prominent knobby leaf scars. Dwarf cultivars, rarely exceeding 1m in height, are now available. In a well grown cassava plant, a cluster of five to ten tubers is produced at the base of the stem (Kochar, 1981).
The leaves tend to be clustered towards the top of the stem as the lower ones are shed.
Cassava is essentially a low land tropical crop, although sometimes it is grown as high as 1830m. It can be grown economically on poor exhausted land (such as in arid regions) and needs little care. Afriable, fertile, well-drained sandy loam is considered desirable. Cassava thrives best in full sun and is susceptible to cold weather and frost. The crop is particularly important in regions where cereals and potatoes will not grow. It is propagated by stem cuttings (22.5-30cm long) which are stunk into the soil just before the rainy season. It is often intercropped with other food crops but may also be planted as a pure stand. Some varieties mature in as little as seven months,while  other may continue to increase in size for up to four years.
If kept too long, tuber becomes rather woody and commercially unimportant. The plants are extremely productive, yielding up to 50t/ha under the best conditions.The tubers are day out individually for home consumption as they keep well in the ground. They spoil quickly after harvesting.
A mature tuber consists of the following three distinct zones, an outer periderm which may be thick and rough or thin and smooth, varying in colour from white to pink, red and brown,a thin cortex or ‘rind’ usually white but streaked with brown in some cultivars and a large white  or cream – coloured pith or core, consisting of a mass of parenchyma in which are embedded a few xylem strands and lactiferous tubes.


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